DESCRIPTION:

5 genes related to SNPs previously identified as being related to opioid-use disorder in humans. A genome-wide association analysis was performed for 21,310 patients of European descent, and SNPs associated with OUD were identified. Data are from Table 4. Values presented are p-values.

LABEL:

GWAS of OUD in humans

SCORE TYPE:

P-Value

DATE ADDED:

2021-06-11

DATE UPDATED:

2024-03-04

SPECIES:

AUTHORS:

Wenyu Song, Joe Kossowsky, John Torous, Chia-Yen Chen, Hailiang Huang, Kenneth J Mukamal, Charles B Berde, David W Bates, Adam Wright

TITLE:

Genome-wide association analysis of opioid use disorder: A novel approach using clinical data.

JOURNAL:

Drug and alcohol dependence 12 2020, Vol 217, pp. 108276

ABSTRACT:

Opioid use disorder (OUD) represents a large and pervasive global public health challenge. Previous genetic studies have demonstrated the significant heritability of OUD and identified several single-nucleotide polymorphisms (SNPs) associated with its prevalence. PUBMED: 32961455
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