DESCRIPTION:
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL). Generated by gene2mesh v. 1.1.1
LABEL:
Steroid 11-beta-Hydroxylase
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
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